The question that most people will immediately have for Colley is why? What makes someone decide to research all things poo for a comedy show? "Purely for the challenge. I mean, has anyone written a joke about poo before? Is it even possible? " She asks. "Poo is a source of secrecy and shame for all of us, but in science we are having a poo Renaissance. After the 20th century being mainly about identifying bad bacteria and killing it, we're now realising how much bacteria is beneficial for us, that it plays a key role in our digestion, hormone production and moods, and we're just at the dawn of understanding how the gut talks to the brain. It's really fascinating, so this was a chance to sink my teeth into the latest research on faecal transplants, studies of the gut microbiome, and confront some of my own biases and fears on poo."